A study was conducted at experimental farm of PC Unit, Sesame and Niger, College of Agriculture, JNKVV, Jabalpur, Madhya Pradesh, during Kharif 2021. Seventy five diverse genotypes of sesame were screened against leaf webber and capsule borer (Antigastra catalaunalis Dup.). The larval population of leaf webber and capsule borer was recorded at weekly intervals started from one week after germination to till maturity of the crop. The highest mean number of larvae per plant was recorded in genotype Prachi (3.10 larvae/plant/week) followed by JTS-8 (2.67 larvae/plant/week) and IC-204200 (2.47 larvae/plant/week). The average number of larvae (0.60 larvae/plant/week) was recorded lowest in SI-250 followed by IS-1672 (1.03 larvae/plant/week) and TKG-306 (1.23 larvae/plant/week). The observation recorded at an interval of seven days varied significantly from each other in respect of average number of larvae per plant. The highest larval population was recorded in between 49^th (3.50 larvae/plant) and 56^th (3.07 larvae/plant) day after sowing which was coincide with the flowering and capsule formation stage of the crop.