Author(s): Dhawal Kant Yadav, Surender Singh Lathwal, Aarti Kamboj, Mohanned Naif Alhussien and Ajay Kumar Dang

Abstract: Immunoglobulins (Ig) are important factors in the immunological activity of milk and colostrum from dairy cattle. The primary immunoglobulin in cow colostrum and milk is IgG, which can bind to a wide range of pathogenic bacteria and viruses. Bovine IgG can exert its effects on several levels, including: Direct effects on potential pathogens, Enhancing clearance of pathogens, Influencing intestinal barrier function, and Modulating immune function. The study was conducted to evaluate the effect antioxidant injections on the levels of total immunoglobulins in the crossbred cattle plasma. Four groups T₁, T₂, T₃ and T₄ were created consisting of six crossbred animals each. Group T₁ was used as control group and was fed only basal diet. T₂ group was injected with multi-mineral injections, T₃ was injected with multivitamin injections and T₄ was injected with combination of multivitamin and multimineral injections. They were injected on 7^th, 15^th, 21^st, and 30^th day before parturition. T₄ group showed the highest increase in immunoglobulin levels in the plasma (p<0.05). T₂ group showed considerable increase also (p<0.05). The increase in immunoglobulin levels of T₃ was also there but not very significant. After the completion of study we found that systemic administration of micronutrients can significantly enhance the immunity of animals as well as their health status whereas oral administration also enhances but at lower levels then systemic administration.

DOI: 10.33545/26174693.2024.v8.i5d.1086